Assuming you have your top all marked out with the designs you want to quilt, I would just put it on the frame and work top to bottom. I usually go left to right on my first pass and come back going right to left on my second pass but it depends on what I am doing. If you view pictures of my post while I was quilting a Wholecloth style on my LA, perhaps this will help. Motifs that fit in my quilting space I did as much as I could then did back fill.
http://www.quiltingboard.com/picture...e-t183485.html
http://www.quiltingboard.com/picture...e-t184163.html
http://www.quiltingboard.com/picture...e-t184706.html