My cat is diabetic and requires insulin shots twice a day. We used to tent camp but bought an RV so we can take him with us when we go. He does fine--he loves laying in the window watching out when we are parked. When we are driving, he sleeps on one of the beds, we have to wake him up when we get home. Before he became diabetic we would leave him home and my sister would check on him, but he would get so lonesome. Now that he is diabetic, we don't want to stress him by leaving him for several days, so he goes with us. I think every cat is unique, though, and will handle it differently. Thankfully he does ok! Good luck with yours.