Thanks for the suggestions and replies. I guess this a very common problem, and it might preclude panels from my future quilting projects. That's a bit disappointing, isn't it, because there are some really cute panels out there.
Anyway, the print goes "off" about midway down and it's more than an inch off from that point to the bottom of the panel. I think what I'll do is just cut it apart (there are three "sections" to the panel) and use it to make a two-sided quilt. I'd also purchased a pack of 5" charm squares to use in the quilt so I'm just going to sew those together to make a square-ish top and then use the panel with some other fabric for the other side.
I think it will be VERY noticeable that the print is so far off, unless I put it off kilter in my design. Then, it might be less noticeable ... I hope ...