I haven't made 50 a year but I have made 20+, 5 of those were queen or larger, in 2012.
I either LAQ mine or have them LAQ'ed.
If I'm working on a labor intensive top, I may take a day or 2 and make something quick to break that thought process. All of my quilts have homes before I start them, and my list always has 3-7 on it, and I would say the majority of mine are used on a regular basis if not daily.
Goes without saying, there is a huge time difference in having a LAQ. I have however, spent 52 hours quilting on one and 46-48 hours on another on the LAQ. Can't even imagine how many months that would've taken by hand.