96 X 104 is the largest I've done so far without sandwiching and quilting in sections. That was on my Babylock with an 8" throat. Working in the very center of the quilt is tight but manageable and I do a lot of FMQ and meandering designs. I always use Warm & Natural or similar batting and that does make a difference. I'm really looking forward to quilting on my new Dreamweaver with the 11" throat. I've got one top ready to go that is 104 X 104. SOMEDAY I would love to own an HQ Sweet 16, but currently have no place for one.