if you want the blocks the same size you could add a simple border to start with making the quilt center 48 x 40 would make it possible to make 8" blocks...or what ever size you would like to make- just add a border first- I have used 9-patch corners with 3 strips of border fabric to 'frame' lots of panels before moving on to blocks- works out well...or any type of border you like that would bring the panel into a size that is easier to work with