My sewing table is my dinning table. It sets in the middle of the room. I drag a chair or coffee table over to keep my quilt from falling on the floor. My sewing machine is a Brother that I purchased on sale at for less than $100. I am able to piece any size top on my machine. I have quilted smaller size quilts but I need to take the bigger ones to the long arm for quilting.
I do not hand quilt but I have quilts that my Mom hand quilted over 50 years ago. We have used these quilts many times over the years and they are not showing signs of falling apart yet.
Just go for it and make your space work for you.