I made a quilt for one of my friends before she went in for her first chemo treatment that was all HSTs. I started out with 10" squares, and squared the HSTs to 9". Each was dark gray on one half and a cheery color on the other half, mostly in yellows. I called it her sunshine and shadows quilt to remind her that life was filled with both and this was just one of the shadows she had to go through to get to the sunshine. She has now been cancer free for over 5 years.