I have painted on fabric with good results. I stretch the cotton, paint with acrylics and fabric medium mixed, then use the panel as a medallion or however you want to. Tell her to paint with thin coats and allow it to thoroughly dry before using it. I did a denim jumpsuit with mice on it this way and it went through many washes without losing the mice. I do think she would be wiser to make a wall hanging than a bed quilt. I could see it in the center of a bed runner. Momm,yum! Post pictures, pleez!