All the quilts are awesome, the only thing that I would be concerned with is how easily is the wool to clean, if she is having chemo I imagine that what ever she uses will have to be cleaned often.
I know that a good quality polar fleece washes and dries really well and if you need a little more warmth you can put something between, though I usually just use the fleece with nothing in the middle, and it comes in different weight, I find that the 10 oz is pretty warm and cuddly. (or you could put it in the middle and still use the fabric for the outside)