Originally Posted by
Prism99
I think it matters only when accuracy is really important for a quilt top.
I'm sorry, I disagree. Accuracy is
always really important for a quilt top. Even if all you're doing is sewing 10½" squares together, setting the seams makes the block size more accurate, more uniform, and therefore the top is more square, and the whole thing looks better when you're done.
I suggest the OP make two four block 'tops' - one made without setting the seams and one made with set seams throughout. She can then decide if she thinks it's worth doing. It's a personal decision.