The best hand cream I've found over the years is Johnson's Baby Lotion. I use it year round. Unfortunately not even it does much good on my fingers when hand quilting. Been doing about 4-8 hrs/day of that for the last few weeks trying to get this baby quilt finished (it's a big baby quilt!) so my fingers are just a breaking, calloused mess at the moment. I'm closing in on the finish so not too much longer and then I can give my poor fingers a break.