Go ahead and Google Retayne. REtayne should be used as a pre-wash. Synthrapol is for quilts after construction. I did not see any health risks when I googled Retayne. I always pre-wash in hot water any fabric I purchase and I use color catchers. Any one can have an allergic reaction to anything. I've not read anywhere of anyone having an allergic reaction. If a product has fragrances or dyes, I can't and won't use it. I hate shopping because of this. And I am always sneezing and coughing in the fabric stores. That is another reason I try to really plan my time in any store.