I have made comfort quilts for folks in many lousy circumstances. See if you can find out what colors she likes ,what kind of personality...ie. girly- girl,outdoorsy,modern,traditional. I make mine light weight( easier to fold up and haul around) with the backing flannel or minky( soft and comfy). I find out how tall they are,and add 12 inches to make the length just right. Mine tend to be bright colors on a white or beige background, simple patterns that are fast to sew up. I FMQ words of encouragement( peace,love,faith. Etc) in the sashing.