as long as your quilt is quilted to the recommendations it will hold up- the batting pulls apart when the quilting density is not adequate. (such as- if the package says you should quilt every 2"-4" and your quilting lines are 6" or more apart- you are going to have a problem down the road with batting separation.
I've been using 80/20 for years- love the stuff. I do often still choose a polyester for kids quilts- because polyester wears so well & takes lots of abuse- is loftier *kids like their quilts puffy- lofty- soft & cuddly* & lighter weight- and I don't always want to quilt as densely as the 80/20 requires- but it holds up fine.