Several years ago, our dog got fleas. I was working on a quilt top in close proximity to him and I went nuts washing everything in site, including the quilt top. It came out perfectly. I don't remember if I used hot water (probably) or cold water. I know I had pre-washed the fabrics, however. I'm with the others. I would take apart and re quilt it and then wash it. However, if it smells really badly and is machine pieced, I would probably consider taking it apart and then washing it in cold water, cool drying cycle.