Fabric Depot is definitely a must-see. There are several excellent quilt shops between Portland and Eugene if you're willing to drive just a little bit off the freeway. One is Purple Frog in Jefferson, another is Finally Together in Lebanon. Both shops are bright and open with lots of light and friendly people to help you. Another really excellent shop that will take you further off course is JanniLou's in Philomath. I think JanniLou's has some of the most varied and interesting shop samples of any shop I've ever seen, totally worth the trip.