since I dye a lot of my fabrics- and have certainly done my share of tie-dyes I say.... of course! go for it! my tie dyes (or any other hand dyes) do not bleed- I use good dyes and rinse them until there is no more fugitive dye left. if you choose a commercial fabric I would test to see if it is color-fast or not- & if not then certainly pre-wash it until there is not bleeding problems. every quilt I make has at least a little bit of fabric I've dyed myself- the tie dyes are fun and a family favorite to play with when designing.