I agree with Francie Y--in doing a remodel, handicap access is an important factor. You may not need it now, but doing so the first time is easier than trying to retrofit. Don't forget doors wide enough for a wheel chair or walker, as well as "tall" toilets and grab bars. Like Athomenow, we have a split level house, 7 steps to everywhere. I have had both hips replaced since retiring. I can do stairs now but couldn't for several months after each surgery. We have installed railings on both sides of the stairs and add grab bars and taller toilet in the bathroom. I vote for main level for the sewing and laundry room.