Welcome to the QB! Yes, you can start small - make a quilted pillow top. Or a baby quilt or a lap quilt for somebody in a wheelchair. My best advice would be to start with a simple pattern - my first project was not simple and is still unfinished in a closet for the past 40 years. You already have a sewing machine so you obviously know how to use it. If you have sewn garments, then you already know how to follow directions. Just remember that most quilt blocks use a very accurate 1/4 inch seam. HTH