What does the little girl like - princesses, butterflies, flowers, etc.? I would find a fabric like that make a 9-patch with a plain square, maybe even making the plain square a snowball block. I've made a couple quilts with princess fabric and pink fabric with crowns to go with the princess motif, or ballerinas, but they were well received and by making the quilt with 2 1/2" strips for the 9-patch, then alternating with a 6 1/2" square, a 5 block row across and 7 down makes a good sized lap quilt with the addition of a narrow border and then a 5-6" border.