I have yet to meet a Janome I didn't like...
I recently bought a 3160QDC as my portable - I think it's sort of a big brother to the DC2013-2014 machines (Instead of "decor", it's "quilters decor") and I love it. It's the purriest machine I've ever had, runs even sweeter than my 6600. I picked that model so I could get the scissor cut button, which is my most favorite button in the whole world!
When you're comparing - make sure you have a list of your "must haves" and "want to haves" and see which machine has the most of each. Check what feet they come with, and other things like an extension table. See which has a better case (if there's a difference). And as Prism said..weight!