There are many who just don't understand (and never will) the value of something handmade and treat it accordingly. We live in an instant-gratification, throw away world, so it's no wonder. The most you can do is be judicious in selecting the recipients of your handwork, as it is wasted on those who are clueless.
Two years ago, I gave my niece a baby quilt for her first baby. Here is what she said when she opened it:
"Oh, that's really cute--it's so BIG!" (I make them bigger so the child can grow into it.) "We can use this for a picnic blanket."
I was upset that she instantly relegated it to a lesser function than what was intended and left me sad that the baby wouldn't get to use it.
Her second baby did not get a quilt.