I recommend getting a Clover Dome Thread Needle Case
http://www.joann.com/clover-dome-thr...4&prefv1=false You can thread multiple needles and load them into this and there is no tangling. When you use all the thread on one needle, pull out a new threaded needle, place the empty needle in the case, and continue sewing. Once you have used all the threaded needles, you rethread and reload and you're ready to go. I also pretreat my thread with Thread Heaven before I load them in.
I use mine when I am doing hand work, red work, binding, applique.