I am retiring within 7 months and moving from Texas to Michigan. I have friends in Texas but I want to be with my family (sisters)in Michigan. I have grandchildren in TN and TX but my widowed DIL is remarrying and I don't want to be a burden to her when I am older.
As for quilting activities, I feel as long as there is a quilt store within driving distance I am okay. A guild in town is a nice plus, too. I will travel to some quilting events, and visit friends and family each year. I have made some solid friendships in my Texas guild and we will probably meet up in Paducah or Houston most years and communicate via the internet. Craftsy offers good classes too.
I think wherever you go you will find what you need.