I have a friend who made the most beautiful hand applique quilt, but mixed up with machine quilting. She appliqued leaves on a block (I believe it was dark leaves on light blocks), then each block was cut diagonally, and resewn to another cut block, giving each one 4 different colors. (two lights on the background, 2 darks on the leaves) It was gorgeous. It was all done in batiks. It was very portable, as each block was worked on by individually. She would carry it all around in a gallon sized zip lock bag.
Best of luck and strength to your friend, and to you as well. Keeping up the visiting schedule will be a challenge. You're a great friend!
M