If you are sewing your binding on by machine, start in the very edge of the quilt, the stitches will be secure and you can FMQ in and out of the seamline. If you are binding by hand, start with 3 or 4 very small stitches and end the same way, staying out of the seam line.
It was just discussed that when you hand sew the binding, your stitches may show due to the quilting in the seam lines. :D:D:D