Follow-up: I just looked at your diagram and did some calculations, and the way it is in your sketch, it would finish at about 63 x 77" with 10" blocks, not 90x 110". Are you going to have other rows beyond what's in the diagram?
Another thing to consider is the placement of the yellow stripes on the bed, not just within the quilt. If the entire quilt is in your diagram, then the yellow stripe at the top will be in the pillow tuck, and the yellow stripe at the bottom might be partly hanging over the foot. If you want them to be visually centred on the bed like in the diagram (which is what I would want), you might have to extend the pattern at the top and bottom a bit.
Also, keep in mind that a queen batting is 90 x 108", so if you make your quilt 110" long, you'll have to buy a king-size batting.
I've quilted a quilt almost that size on my domestic machine. It isn't easy, but is quite doable as long as you stick to straight-line quilting. I've also since read about cutting batting into sections, which reduces the bulk. Good luck!