I use Isacord. I usually have a color scheme in mind, and poly has a lot more colors, especially in shades.
All the machines like it. I embroider with a Pfaff 2170, but I've put it on the PQ 1500 for quilting.
The one thing that convinced me - metallic thread. I watched a big 830 at the Bernina dealer going full speed and using OESD YMNET thread ( Bernina owns that) . It never broke and did the whole design with no hitches.
I bought that Madeira chest long ago, and didn't use 85% of the colors. I sold it.