Thank you for all the suggestions. I think you will all agree that the first thing to do is try to replicate the stain, both with the silk flowers and hopefully with a scrap of the red fabric. Then I'll try your suggestions for removing those stains before doing anything with the quilt. I want to do my best not to ruin the whole quilt since I have a lot of time and money invested in it. A local church group did the hand quilting and did a beautiful job. I'll let you know how it turns out.