Respectfully disagree with CathyVV ... I did learn EQ 99% by winging my way through. Every now and then I would pick up the book or ask a QB member how to do something.
That said, I've designed mostly basic stuff. Blocks and whole quilts, straight and on-point, with and without borders. I have also scanned some of my own fabrics into it to use. I've not tried bargello or appliqué, and I don't use it at all for quilting designs (not yet anyway).