Of course it's possible!
This page has a couple of pretty examples
http://quiltinspiration.blogspot.com...uilt-show.html
Bella Bella Quilts by Norah McMeeking are just awesome and are still available.
https://www.google.com/?gws_rd=ssl#q...orah+McMeeking
A lot of the paper pieced patterns look like the Mosaics, especially Jacqueline de Jonge's and some of Judy Niemeyers.
It will be fun to see what you decide to make.