I've rearranged my room so that my design wall is directly behind me as I sew. Makes it really convenient to just peel a block off the wall and sew it together. I can cut it all, bring it to the wall and arrange it there to make sure it's all in the right order, then just sit and sew it all together, putting finished blocks back up on the wall.
Works as long as I'm just doing a small section. Still have to get up a lot if I have a whole queen-size laid out on there, lol.