I live in W-S, right on the edge of Clemmons. When I moved here 3.5 years ago, I was excited by the number of quilt shops but sadly disappointed after a while. The hours are very restricted, so if you work, it's hard to frequent them. The prices are high and the selection not terribly good at several. If you have the shop in your house, you could keep prices lower because of less overhead. I would suggest a strong online component too. I know someone in NY who has done that and she is doing quite well. I always visit her shop when I am near.
She also does LAQ. I'm not sure if there is anyone locally in NC that offers LAQ. I still have my done in NY since my DH still lives there and I am back feprequently. He will be moving this year and it would be great to find someone in NC.
So my answer is good selection, lower prices, evening hours and online presence. Please post if you decide to go ahead. I'll certainly come to shop.