Franklin has some nice quit shops. Franklin is about 15 minutes south of Nashville on I65.
If you want to visit a shop has more fabric than you can shake a ruler at go to Stitcher's Garden. The atmosphere isn't the cheeriest, but it's worth the stop just to see it. Myra never has a sale. She never marks her fabric up either. So if you're patient there is fabric for 8.95/yd. Hopefully Bridget will be there to assist you. Give yourself at least an hour. (Myra turns the lights out promptly at 5 pm.)
It's in the shopping center section that is parallel to HWY 96/Murfreesboro Rd. It's right off I65 at the Hwy 96 Exit (Franklin/Murfreesboro) in Franklin (south of Cool Springs Galleria mall). Exit the freeway, turn right, turn left at the McDonalds light. The shopping center will be about 1/8 mile on your right.
Watson Glen Shopping Center, 209 South Royal Oaks Boulevard, Franklin, TN 37064
(615) 790-0603
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Kentucky is supposed to have a few nice shops around Louisville, but I haven't made it there yet.
Elizabethtown, KY has a nice shop, but it's about a 15 minute drive off the freeway.
https://uniquequilts.wordpress.com
Whittles is a discount shop in KY about 10 miles off the Corvette Exit on I65.
http://www.whittlesfabrics.com/
Make sure the shops are open before you take the back roads. It's a pretty drive though.
I'm headed to southern AL and was surprised it has mostly garment and upholstery fabric shops. Check out my post earlier this month about Shops on coastal AL. There are a few not too far out of your way.
Have a safe trip!