As I understand, the 750 doesn't have layers when you're doing embroidery, and the 780 does. Which means that if you want to put a name with a design, you'd have to embroider them out seperately on the 750. But with the 780, you can combine them on the screen, and can work with several layers at a time on one project. They both come with the regular software. If you wanted to add software, you'd add the digitizing software, which makes it so you can scan something and turn it into an embroidery design. Most people don't need that.