If your machine will sew it, you are free to use it in any way you wish. It'd be neat to mix it up with corduroy, linen, even velvets. you could even dye some of it to have a range of colors. nice to have a quilt with some weight to it this time of year...some of ours tho lovely, really aren't as warm as i'd like them to be. Keep in mind how it will be washed but once quilted, the suede should do fine.