Because of the thickness of the skin, I would use as big of pieces as possible, keeping the seams to a minimum. I would probably add a similar thickness of fabric and use simple squares with a random pattern. Since it is an animal skin, the thought of backing it with sherpa keeps coming to mind....very warm, minimal quilting necessary, no batting needed (could even be tied). Whatever you choose, plan well and sew carefully as the needle holes are forever. Please take good pics and show us!