I am ambidextrous, but can't switch doing most things from one hand to the other. I eat and write left-handed, cannot do either right handed. I bowl and bat right handed, cannot do with left. I pin right handed, cut left handed. My DD is right handed and has said my cutter is set up the same way hers is. The only problem I've really found is rulers are backwards for me. Unless I use the ruler bottom-end up, I have to transpose the measurements to cut. Sometimes I need to read directions with pictures in them several times to make sure I'm doing it correctly.