I used a fleece blanket on one of my very first quilts, before I knew the Quilt Police would frown on it. Since it was a blanket, I didn't have to piece it, and my son loves it. It's warm and drapes/cuddles nicely. When my son was small, he had a medical issue that made him wet the bed almost every night, so there was a LOT of washing of his 2 quilts for a couple of years. One was a flannel quilt with muslin backing. The other was cotton with the fleece blanket backing. The flannel quilt is very worn and the fleece quilt looks almost new.