As a former dialysis patient (thank God for good friends who are willing to donate a kidney!!!) I would be careful what you make the quilt out of. I would use something that would take lots and lots of washings. You never know what will get spilled or splattered on the quilt. You do get very cold on dialysis and I found the warmest thing to cover up in was fleece. Maybe you could back it with fleece or make the whole thing fleece. I don't want to take away from your creativity but keep in mind this will be used, abused, dropped on the floor, spilled on and generally worn.