Yes. I made an Hawaiian theme quilt from men's shirts I bought at the thrift store. I use flannel sheets for the middle and back of rag quilts, it is better quality than I can buy by the yard. I buy from yard sales and thrift stores, but I wash them in hot water and dry on high as soon as I get them home. If I can't get to it right away I leave them outside in a trash bag to bake.