I do rag quilts that way. I have quite a few quilting patterns that came on software, and I have Quiltworks, which will do anything I can draw. Sashiko patterns also work. Holds top, flannel and backing together nicely.
I can only do 5X5 comfortably on machine (It will do 12x12 but you need to reverse hoop) so I wind up using 8" blocks. I learned to do some FMQ for a raggy with special fabric. The fabric was the star of the quilt and not the quilting. Made stencils of what I had on the computer and put designs on gold paper.