I agree with everrything that has been said, and i have used all of the above mentiones lotions and cremes. Its a constant on going problem. I also prewash all my fabric and my hands still get dry and cracked. My dermatologist suggested the Cervae creme which works well, most drugstores sell it. Large jar and alittle pricey but worth it. I do buy vinyl gloves to wear a lot and that helps. Good luck in finding what works for you