What size itty-bitty to you?
When you have not shared any info as to what sort of a pattern you are doing, it's hard to know what tips might help.
No matter what you are doing, IMHO making sure that the single hole plate is in your machine can make a big difference to end quality.
Some use tweezers when doing small work.
Sometimes it helps to oversize and trim down to keep all square ... again, without knowing what you are doing, unknown whether this is even a possibility.