Sure you will! I've done a large queen on my DSM, just did straight line serpentine stitch, but got it done. It was not easy, I use thin 80/20 batting, glue basted, rolled it to be able to start in center, used large safety pins to help hold it into roll. I also have a folding banquet table that is my sewing/cutting table, I cleared it off, pulled it up to left side to hold weight of quilt. Also have a hospital overbed table behind my machine that is perfect to catch it as you feed it through, and also helps a lot with holding the wieght of it.