You definitely have to decide on the layout before you'll know the answer to your question. When I started my first project, I just made the flowers,rosettes, whatever, with one in center, six surrounding, then after I had a lot of them made, I spread them out and decided on layout, had looked at several for ideas. Here is a link to my first one, just know that you've been warned, very addictive!
http://www.quiltingboard.com/picture...d-t257980.html