I use Warm & Natural and hand quilt it all the time. I've not used any other battings so can't offer an opinion. If I ever get through the roll that I have I probably will try Quilter's Dream. I don't mind the heaviness of W&N...I like the weight. I do not have one of my quilts on my bed but would use W&N for that as well. I do have 100% cotton blankets and spread about the weight of W&N because I DO like heavy covers. I don't find W&N all that difficult to hand quilt but then again, it's all I know. And like others have said, does not have to be densely quilted which sometimes is an advantage.