YES!! I made a scrappy flying geese quilt about 30 years ago that was batted with polyester, which I now never use -- I personally hate it for weight, appearance after quilting (very little in this case), and the way it feels too warm under it.
I spent hours taking it apart about 5 years ago because I never used it any more, yet loved the colors in it, especially how the blues have faded a bit over time, and wanted to love using it again. I will batt it with Quilters Dream cotton or Hobbs cotton and add much more quilting than the straight line row quilting I did then.
The top has held up very well and would look almost like new except for the fabric patterns and that fading.
Jan in VA