I have made a number of quilts for children and for the elderly. Both give quilts a good work out but I have not done anything different for these quilts that I do for other quilts. Good fabric, good thread and away you go. Guess I might avoid a patter with small pieced cuts but goodness there are so many patterns to choose from. Go for it and enjoy the ride. Besides, when they "wear it out" they will come to you and ask for another because their quilt was so special and from you!